arotrios

joined 5 days ago
[–] arotrios@kbin.earth 28 points 1 hour ago (2 children)

Ok kids. Let me take you back in time to the olden days of yore, or as we like to call it, Wednesday morning.

Back then, a little known user, @dgdft@lemmy.world, posted an innocuous shitpost regarding early Mr. Universe winner, Bruce Randall:

https://kbin.earth/m/lemmyshitpost@lemmy.world/t/3329134/In-the-late-1950s-early-Mr-Universe-winner-Bruce-Randall#comments

Bruce bulked up by putting powdered milk in his milk. This grabbed Lemmy's attention by the beans and resulted in the memegasm of powdered milk we see today. Last time I checked, it had blown it all the way up to Ten Forward:

https://kbin.earth/m/tenforward@lemmy.world/t/3330101/This-substance-is-inefficient#comments

...where apparently resistance to powdered milk is futile.

These days (Wednesday evening), the powdered milk memegasm has mostly run its course. Metamemes are popping up, blending beans and milk, with dire consequences for Lemmings' digestive systems and anyone standing downwind of them.

In essence, powdered milk is a prime example of the meme lifecycle - arising from a shitpost, wafting high on its own cringe into the collective consciousness to be flung between hairless apes until it splatters over everything, marking everything with its scent before finally descending back into the shitpost from whence it came.

Side note: This would make a perfect subject for a documentary on memes narrated by David Attenborough.

 
[–] arotrios@kbin.earth 32 points 8 hours ago (3 children)
[–] arotrios@kbin.earth 5 points 9 hours ago (2 children)

What about ghosts? They're human.

[–] arotrios@kbin.earth 51 points 9 hours ago (5 children)
[–] arotrios@kbin.earth 1 points 9 hours ago

Fit Nick - will knife you for cigs

[–] arotrios@kbin.earth 15 points 9 hours ago

Oh how the turntables...

[–] arotrios@kbin.earth 1 points 11 hours ago

Pregnancy is the gotcha gatcha.

[–] arotrios@kbin.earth 2 points 12 hours ago

Who is this Valdovinos and why is he painting me?

[–] arotrios@kbin.earth 36 points 12 hours ago (2 children)
[–] arotrios@kbin.earth 25 points 13 hours ago

Slow walking the transformation of a discussion forum into a propaganda machine...

[–] arotrios@kbin.earth 20 points 13 hours ago

Company that built the torment nexus declares that the nexus may torment. Stock prices rose on the news.

 

Abstract:

Over the past 5 to 7 million years, humans and chimpanzees have diverged in brain size, structure, and cognition despite high conservation of protein-coding genes. However, retroviral infections within host genomes have introduced numerous species-specific regulatory elements. Chimpanzees harbor lineage-specific PTERV1 endogenous retroviruses that are absent in humans, but their role in brain evolution has remained unclear. We performed an epigenomic analysis of PTERV1 insertions in chimpanzee neural organoids and found they are heavily DNA methylated, forming over 150 species-specific heterochromatin domains with the potential to influence gene regulation. We identified a chimpanzee-specific insertion on chromosome 19 that silences the long noncoding RNA LINC00662 through DNA methylation spreading. CRISPR-mediated deletion of this PTERV1 restored LINC00662 expression in chimpanzee induced pluripotent stem cells. We show that LINC00662, a human-specific transcript expressed during brain development, plays a role in neuronal maturation, axon outgrowth, and neural organoid development. These findings reveal a mechanism by which endogenous retroviral insertions contributed to human-chimpanzee brain divergence.

 
view more: next ›