this post was submitted on 10 Mar 2026
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I unfortunately live in a not very trans friendly state in the US (more like trans hostile tbh) so I've been doing my HRT pretty much solo/without seeing doctors. Been doing mono estradiol enanthate for about a year now following the manufacturer's recommendations (0.15 mL every 7 days) and wanted to try getting on prog but i'm not sure what dosage i should be at. any recommendations?

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[–] applebusch@lemmy.blahaj.zone 0 points 7 months ago

Just wanted to say I do 5mg estradiol valerate once a week intramuscular and 100mg progesterone rectally every day. I found this had all the expected effects before getting my levels checked, and getting my levels checked showed I had estrogen levels on the high end of the expected range and my testosterone was sufficiently suppressed even being a little below the normal cis woman range. I'm really happy with my results so far and was pleasantly surprised that this dosage is what I was prescribed from the beginning. I went to planned parenthood, and while some of their recommendations are a little dated (they said subcutaneous injections and taking progesterone rectally weren't recommended) I'm happy they at least had reasonable doses and didn't make me jump through hoops to get it. If anything I think I might want to go up in dosage on the progesterone because I haven't really had the increased libido people talk about.