this post was submitted on 24 Jul 2026
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Is it safe?

I know estradiol pills fuck liver so I can fix this problem by switching to injections but I wonder if this is the case with progesterone?

I can't do the buffing stuff every night, sorry lol.

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[–] Moxie@lemmy.blahaj.zone 0 points 5 days ago (3 children)

You can inject progesterone! Some suppliers sell estradiol and progesterone combined in a single vial.

[–] sidalsolgun@lemmy.ca 0 points 4 days ago (1 children)

Isn't this how you become paralyzed?

Or was it a pill that caused it, can't remember now?

There was a "all in one" pill a Turkish trans woman got and became paralyzed in Türkiye. You can find it on pubmed.

[–] will_steal_your_username@lemmy.blahaj.zone 0 points 4 days ago (1 children)

No. It's a very common injection in some parts of the world. Bioidentical prog and e won't paralyze anyone

[–] sidalsolgun@lemmy.ca 0 points 4 days ago (1 children)

Where to find 2-in-1 versions?

DIY?

I've not seen them available on the sites I've looked at but my understanding is it's fairly common in latin america as a form of birth control for cis women. The prog might not be bioidentical in the injections, but even then the side effects shouldn't be paralysis.

[–] erinmeow@piefed.blahaj.zone 0 points 4 days ago

wait, aint that acting only 24 hours? prog injections usually are daily but sythetic ones can can be used for week(i didnt remember), so some esters of bioidentical prog exist?

[–] Arkhive@piefed.blahaj.zone 0 points 4 days ago (1 children)

I’m very interested in this. Any chance you have additional info on the options?

[–] Moxie@lemmy.blahaj.zone 0 points 3 days ago

Another option is ready-to-use solution of estradiol valerate 50 mg and progesterone 250 mg, 20 USD/vial, 8 to 16 vials per packet. Custom EV/P ratio is possible, or EV + hydroxyprogesterone caproate.

http://lena.kiev.ua/EV/