Danger Dust - What Else?

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A community for those occupationally exposed to dusts, toxins, pollutants, hazardous materials or noxious environments

Dangerous Dusts , Fibres, Toxins, Pollutants, Occupational Hazards, Stonemasonry, Construction News and Environmental Issues

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Bampot@lemmy.world

Specific features of immune ageing are detected in the earliest stages in rheumatoid arthritis development (www.thelancet.com)

submitted 10 months ago by Bampot@lemmy.world to c/dangerdust@lemmy.world

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A senolytics trial in human idiopathic pulmonary fibrosis patients selectively ablating senescent cells using Dasatinib and Quercetin (DQ) alleviates physical dysfunction and circulating SASP factors which have been confirmed in a cohort of inflammatory disease.

Our data provide a rationale for trials of such anti-ageing drugs in patients with arthralgia at risk of developing RA which can be validated in future preclinical and clinical studies to explore dosing and treatment duration to delineate the therapeutic window and maximise therapeutic benefits of proposed geroprotective drugs.

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