this post was submitted on 08 Apr 2026
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[–] renzhexiangjiao@piefed.blahaj.zone 26 points 3 days ago (3 children)

ah so it's one of those articles whose title is missing "in mice"

[–] stray@pawb.social 3 points 2 days ago

The "in mice" part is actually really exciting to me because male pet mice have to be kept solitary to prevent pregnancies and aggression with other males, but they still have social needs. It would be amazing if they could be kept with females full-time with no pregnancy risk.

Would also be nice to keep mixed-mischiefs of rats since their personalities and behaviors are somewhat sexually divergent. You could have a couple busy girls and a couple cuddly boys without having to take turns free roaming.

[–] jqubed@lemmy.world 7 points 3 days ago (1 children)

And I question how viable it is given this:

To achieve this, scientists used JQ1, a small molecule inhibitor originally developed to study cancer and inflammatory diseases. While JQ1 is not suitable as a treatment due to neurological side effects, it is known to interfere with a stage of meiosis called prophase 1. This allowed researchers to demonstrate, for the first time, that targeting meiosis can safely and reversibly shut down sperm production.

It sounds like calling the treatment “safe” might be a bit of a stretch.

[–] stray@pawb.social 2 points 2 days ago

I think they meant "safe" with regard to reproductive ability. It sounds like they're happy with targeting meiosis, not with using JQ1 specifically.

[–] kbobabob@lemmy.dbzer0.com 6 points 3 days ago (1 children)

Aren't pretty much all of these medical discoveries from mice?

[–] Redjard@reddthat.com 4 points 3 days ago

It's an early step. Good chance it doesn't work well in humans, and many side effects can't be discovered until human trials either.